In June, we went to deliver 2 teacher training programs in Guyana in collaboration with the Science Unit of the National Center for Educational Resource Development (NCERD), and supported by the St. Stanislaus College Board of Governors. The 4th Pueblo Science workshop was held at the New Amsterdam Secondary School (Region 6) and at the Watooka Complex (Region 10) from June 17–24, 2019. The Pueblo team worked alongside the local coordinating team in Guyana to prepare the 2019 version of the Pueblo Science manual which included activities linked to the Caribbean Secondary Education curricula for the sciences. In addition to the curriculum linkages, the materials required for each experiment, an explanation of the theory of the experiment with discussion and diagrams that guide the setting up of the experiments, are also included in the manual. These activities are fun-filled, hands-on science activities utilizing low cost readily available materials to initiate interest in STEM. The manual also models the inquiry-based science education approach through this 5 E (Engage, Explore, Explain, Elaborate, and Evaluate) instructional design model.